Kuo-Hsiung Yang, M.S.
kuo.yang (AT) ucsf.edu
Seeking post-Pharm.D fellowship positions in industry, particularly early phase clinical trials / PK/PD.
Education and Training
2006 - Present Pharm.D Candidate, 2010, Pharmaceutical Sciences Pathway
2004 - 2005 M.S. Biology, Developmental Neuroscience
2000 – 2004 B.S. Biology, Animal Physiology / Neuroscience
Professional Licensure/Certification
2007 – Present Pharmacy Intern
2007 – Present Basic Life Support / Cardiopulmonary Resuscitation
American Heart Association
2006 – Present Immunization Certification
Professional Experience
2007 – Present Pharmacy Intern, Inpatient and Outpatient
Kaiser Permanente,
Provided patient counseling on medications at both hospital discharge and in a retail environment. Completed automated pyxis machine refills and patient cassette refills. Filled, checked, and dispensed prescriptions. Also conducted periodic audits of controlled narcotics for DEA compliance.
Preceptors: Tam Hoang, Pharm.D and Geoffrey Reeves, Pharm.D
2005 – 2006 Technical Analyst, Regulatory Affairs
Amphastar Pharmaceuticals, CA
Prepared and compiled documents for Abbreviated New Drug Application (ANDA) FDA submissions. Optimized Standard Operating Procedures (SOP) for company operations. Conducted primary literature search for Investigative New Drug Applications (INDA).
Research
2009 Glutathione-S-transferase polymorphism may predict response to Acute Myelogenous Leukemia (AML) chemotherapy treatment.
Pharmaceutical Sciences Pathway Project
Conducted statistical analysis on patient survival and toxicity due to genetic polymorphism in glutathione-S-transferase. Searched primary literature to identify candidate genes responsible for response to chemotherapy treatment for AML, with a special interest in busulfan metabolism and disposition. HapMap database was used to select tag-SNPs (single nucleotide polymorphism) for genotyping by obtaining genotypic data from various ethnic populations. Used GEO (gene expression omnibus) to obtain and analyze gene expression and phenotypic data from microarrays. Compiled survival and other clinical phenotypic data from medical records for genetic correlation studies.
Preceptors: Kathleen M. Giacomini, Ph.D. and
Charalambos Andreadis, M.D.
2007 OCT-2 Transporter polymorphism and response to metformin treatment in healthy patients.
Pathways to Careers in Clinical and Translational Research (PACCTR) Fellowship Project
Reviewed and submitted clinical research protocols for institution review board (IRB) submission. Learned basic study design techniques and relevant statistical issues. Received Training in Clinical Research (TICR) completion certificate.
Preceptor: Kathleen M. Giacomini, Ph.D
Publications
2009 KH Yang, SW Yee, C Andreadis, and KM Giacomini
Busulfan Pharmacogenetics Pathway
Pharmacogenomics Knolwedge Base (PharmGKB)
Online Database (In Submission)
2009 S. Euteneuer, K.H. Yang, E. Chavez, et.al, Glial cell line derived neurotrophic factor (GDNF) signals via both neuronal cell adhesion molecule (NCAM) and the receptor-tyrosine kinase Ret in the inner ear’s spiral ganglion. Journal of Neurochemistry (In Submission)
Clinical Rotations
2009 (In progress) Leukemia, Bone Marrow Transplant
Preceptor: Courtney Yuen, Pharm.D, BCOP
2010 Long Term Care
(To be completed) Laguna Honda Hospital,
Preceptor: Michelle Fouts, Pharm.D, BCPS, CGP
2010 General Medicine
(To be completed)
Preceptor: Eunice Tam, Pharm.D
Honors & Awards
2007 Pathways to Careers in Clinical and Translational Research (PACCTR) Fellowship
This fellowship provided an introduction to clinical research and stimulated students to acquire further training in clinical research. Fellows were required to take courses (Designing Clinical Research and Responsible Conduct in Research), choose a faculty mentor at UCSF and complete a research project. Recipients of this fellowship must have submitted a complete research proposal for consideration.
Community Service
2007 – 2008 Phi Delta Chi Pharmaceutical Fraternity, Treasurer
Organized fundraising activities for community service purposes. Managed finances for ongoing operations.
2004 – Present Make-A-Wish Foundation
Lead wish team to interview families and coordinated the wish granting process.
Special Skills
STATA Statistical Software
WinNonlin Pharmacokinetics Software
Chinese Mandarin Fluency in Speaking and Reading